Name an antibiotic that inhibits cell wall synthesis.

Name an antibiotic that inhibits cell wall synthesis.

• A. Tetracycline
• B. Ciprofloxacin
• C. Penicillin
• D. Erythromycin

Answer: (C)

Penicillin is an antibiotic that specifically targets and inhibits cell wall synthesis in bacteria. Its mechanism of action involves binding to and inactivating penicillin-binding proteins (PBPs), which play a critical role in the final stages of peptidoglycan synthesis in bacterial cell walls. This disruption leads to the weakening of the cell wall, ultimately resulting in bacterial lysis and death. Understanding that penicillin is structurally similar to a component of the bacterial cell wall allows it to competitively inhibit the enzymes responsible for cross-linking the peptidoglycan layers. As a result, penicillin is particularly effective against gram-positive bacteria, which have a thick peptidoglycan layer, making it crucial in the treatment of various bacterial infections. Other antibiotics listed, such as tetracycline and erythromycin, work through different mechanisms—tetracycline targets protein synthesis by binding to the ribosomal subunits, while erythromycin also inhibits protein synthesis by interfering with the ribosome’s function. Ciprofloxacin, on the other hand, inhibits bacterial DNA gyrase and topoisomerase IV, crucial enzymes for DNA replication and cell division, but it does not affect the bacterial cell wall. Thus, penicillin stands out for its specific action

Penicillin is an antibiotic that specifically targets and inhibits cell wall synthesis in bacteria. Its mechanism of action involves binding to and inactivating penicillin-binding proteins (PBPs), which play a critical role in the final stages of peptidoglycan synthesis in bacterial cell walls. This disruption leads to the weakening of the cell wall, ultimately resulting in bacterial lysis and death.

Understanding that penicillin is structurally similar to a component of the bacterial cell wall allows it to competitively inhibit the enzymes responsible for cross-linking the peptidoglycan layers. As a result, penicillin is particularly effective against gram-positive bacteria, which have a thick peptidoglycan layer, making it crucial in the treatment of various bacterial infections.

Other antibiotics listed, such as tetracycline and erythromycin, work through different mechanisms—tetracycline targets protein synthesis by binding to the ribosomal subunits, while erythromycin also inhibits protein synthesis by interfering with the ribosome’s function. Ciprofloxacin, on the other hand, inhibits bacterial DNA gyrase and topoisomerase IV, crucial enzymes for DNA replication and cell division, but it does not affect the bacterial cell wall. Thus, penicillin stands out for its specific action